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MIX-A Series Resins

MIX-A Captarose HF is an affinity chromatography medium where functional groups like phenyl rings and quaternary amines are bonded to a highly rigid agarose base. Meanwhile, MIX-A Captarose HR involves bonding these same functional groups to a high-resolution, highly rigid agarose. The MIX-A series belongs to the category of composite strong anion exchange chromatography media, exhibiting a certain level of tolerance to salt ions. When used for antibody purification, it's commonly employed in a flow-through mode, effectively removing aggregates, host proteins, nucleic acids, endotoxins, and shed protein A from the antibodies.
Product Type Prepacked columns Resins
Pack Size 1mL 5mL 10mL 25mL 100mL 500mL 1L 5L 10L
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Product

MIX-A Captarose HF

MIX-A Captarose HR

Features

Exhibit a certain level of tolerance to salt ions, Fast flow rate

Exhibit a certain level of tolerance to salt ions, High resolution

Application

The capture and intermediate purification stages of biomolecules, effectively removing aggregates, host proteins, nucleic acids, endotoxins, and shed protein A from the antibodies

The intermediate and fine purification stages of biomolecules, effectively removing aggregates, host proteins, nucleic acids, endotoxins, and shed protein A from the antibodies

Matrix

High-rigidity agarose

Particle size

75 μm

40 μm

Functional group

Phenyl ring, Quaternary amino

Metal ion loading capacity

90-120 μmol Cl-/mL resin

80-110 μmol Cl-/mL resin

Flow velocity

90-500 cm/h

90-300 cm/h

Max. pressure

<0.5 MPa

pH stability

3-12(operational), 2-14(CIP, short term)

Chemical stability

Stable in commonly used buffer solutions:8M urea. 6M guanidine hydrochloride, 70% ethanol, 30% isopropanol, 1M NaOH, 1M acetic acid

Storage conditions

20% ethanol; 4-30℃

Pack size

Cat. No.

MIX-A Captarose HF

MIX-A Captarose HR

1ml XTrap Prepacked columns

HC5010011

HC5010111

5ml XTrap Prepacked columns

HC5010012

HC5010112

5ml XScreen Prepacked columns

HC5010013

HC5010113

10ml

HC5010000

HC5010100

25ml

HC5010001

HC5010101

100ml

HC5010002

HC5010102

500ml

HC5010003

HC5010103

1L

HC5010004

HC5010104

5L

HC5010005

HC5010105

10L

HC5010006

HC5010106